The Role of Systemic Oxidative Status in Coronary Arterial and Peripheral Venous Blood of Patients with Unstable Angina Pectoris

(1) Background: We aimed to analyze the oxidative status of patients with unstable angina pectoris (UA), as well determine correlation these parameters between coronary arterial and peripheral venous blood samples. (2) Methods: The study included 47 human subjects UA 45 control subjects. performed clinical examinations, hemodynamic angiography measures. Also, in samples, we measured routine laboratory markers concentration pro-oxidants: index lipid peroxidation (TBARS), superoxide anion radical (O2−), hydrogen peroxide (H2O2) nitrites (NO2−), while antioxidant were determined from red cells: reduced glutathione (GSH), catalase (CAT) dismutase (SOD). All spectrophotometrically. (3) Results: Significantly higher values TBARS all antioxidants SOD, CAT GSH observed group relative On other hand, a significantly lower value was found compared control. (4) Conclusions: This has shown that majority changes redox are blood, especially related activity components. In an form angina, prooxidants (superoxide peroxidation) endogenous (catalase, glutathione) direct course ischemic disease. Future studies, where participants would be randomized depending on symptom duration, necessary confirm conclusions.